Which drug is responsible for causing pigmentary retinopathy?

Which drug is responsible for causing pigmentary retinopathy?

• A. Chlorpromazine
• B. Indomethacin
• C. Thioridazine
• D. All of the above

Answer: (D)

Pigmentary retinopathy refers to a disorder of the retina characterized by the deposition of pigment in the retinal layers, which can lead to vision changes and impairment. Chlorpromazine and thioridazine, both antipsychotic medications, have been well-documented as causes of pigmentary retinopathy. These medications belong to a class known as phenothiazines, which can affect retinal health by causing changes in retinal pigment. Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID), has also been associated with pigmentary changes in the retina in rare cases. Although primarily used for its anti-inflammatory properties, the retinal side effects highlight the potential for pigmentary retinopathy with this medication as well. Given this information, the option indicating that all of the listed drugs can cause pigmentary retinopathy is correct. Each of these drugs has the potential, either commonly or more rarely, to cause these retinal changes, leading to the conclusion that they all contribute to the risk of developing this condition.

Pigmentary retinopathy refers to a disorder of the retina characterized by the deposition of pigment in the retinal layers, which can lead to vision changes and impairment. Chlorpromazine and thioridazine, both antipsychotic medications, have been well-documented as causes of pigmentary retinopathy. These medications belong to a class known as phenothiazines, which can affect retinal health by causing changes in retinal pigment.

Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID), has also been associated with pigmentary changes in the retina in rare cases. Although primarily used for its anti-inflammatory properties, the retinal side effects highlight the potential for pigmentary retinopathy with this medication as well.

Given this information, the option indicating that all of the listed drugs can cause pigmentary retinopathy is correct. Each of these drugs has the potential, either commonly or more rarely, to cause these retinal changes, leading to the conclusion that they all contribute to the risk of developing this condition.